|IDV|SQV|RTV|NFV|APV|FPV|LPV„RTV|ATV

Name of drug IDV
Generic name Indinavir
Trade name Crixivan
Dosage from design White, hard capsule
Symbol CRIXIVAN 200mg

Active ingredient

 1 capsule contains 200mg of IDV
Storage Room temperature, No humidity (Place in a bottle containing a desiccator)

Dosage

Take 4 capsules 3 times daily (every 8 hours).

Take the drug on an empty stomach: Take the drug at least an hour before, or two hours after a meal.
Side effects
  • Nausea (14%): because this drug is taken on an empty stomach, you might feel nauseated or even vomit. This can be somewhat alleviated if you eat low fat food like rice or noodles before taking the drug.
  • Increased bilirubin levels in blood (9%)
  • Kidney stones (9%): IDV (indinavir) itself could form a kidney stone. The symptoms include pains in the back and abdomen, as well as pains while urinating and blood in urine.
    One preventative measure is to drink lots of water, especially right before going to bed because the stones often develop while sleeping.
  • Blood in urine (9%)
  • Ureteral calculus (5%)
  • Back pain (4%)
  • Diarrhea (3%)
  • Bleeding tendency (Frequency unknown)
    Patients with hemophilia might experience increased tendency of bleeding. Record the amount of blood products
    you use and keep a close eye on any changes you might notice.
  • Lipodystrophy (1%)

  • The frequency of side effects occurrence is based on domestic results, at the time of approval for the usage of drugs, and the results obtained by the usage of drugs.
Cautions
  • Beware of high calorie, fat and protein food: the drug will not be well absorbed if taken shortly after eating these sorts of food.
  • Do not take IDV with grapefruit juice since it can lower the drug concentration in blood.
  • Drink enough water: to prevent kidney stones, the main side effect of IDV, drink at least 1.5 liter of water in addition to the regular amount you would take throughout a day.
  • If you are on ddI (didanosine), IDV should be taken two hours before or after taking ddI.
  • Some drugs cannot be used in combination with IDV or need to be treated with caution, thus please obtain a "List of Contraindications on Combined Usage of Drugs and Drugs Requiring Caution."


 

Topics

Lipodystrophy:

For those who are taking the protease inhibitor, you may have a change in your body figure and may have impaired glucose tolerance and lipid metabolism disorder.
If you develop hypercholesterolemia and hyperglycemia, or the loss of fat from your arms, legs and face while your trunk gains fat after several months to several years from the start of taking the drugs, please consult your doctor.
Price

124.70 yen for 200 mg
For a daily dose of 2400 mg, the drug costs 44,892 yen for 30 days.